MACS® GMP Recombinant Human IL-3
Description Interleukin 3 (IL-3) is a hematopoietic growth factor which is produced mainly by activated T cells, but is also secreted by other cell types, including mast cells, eosinophils, and keratinocytes. The broad spectrum of biologic activities of IL-3 includes the stimulation of the proliferation and differentiation of immature pluripotent hematopoietic stem cells and various lineage-committed progenitor cells, leading to the production of most of the major blood cell types. MACS GMP Recombinant Human IL-3 is lyophilized without carrier protein or preservatives. A lot-specific certificate confirms identity, molecular mass, specific activity, sterility, purity, endotoxin content, host-cell DNA content, and host-cell protein content. Applications MACS GMP Recombinant Human IL-3 can be used for a variety of applications, including the ex vivo cultivation of human plasmacytoid dendritic cells from enriched CD304 (BDCA-4)+ cells.1-3 MACS GMP Recombinant Human IL-3 is not intended for human in vivo application. Quality Statement MACS GMP Recombinant Human IL-3 may be used for research or ex vivo cell culture processing. MACS GMP Recombinant Human IL-3 is manufactured and tested under a certified ISO 9001 quality system and in compliance with relevant GMP guidelines. It is designed following the recommendations of USP <1043> on ancillary materials. No animal- or human-derived components are used for manufacturing.

Search this website

Advanced search